Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | METAP2 | P50579 | 2/20 | 0.43 |
| ▸ | CYTH2 | Q99418 | 2/20 | 0.42 |
| ▸ | MMP14 | P50281 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.40 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8631496 | 0.88 | MAPK14 (0.43) | FFAR4CYTH2TSHRKDM4E | |
| SCHEMBL8759199 | 0.88 | CYP17A1 (0.45) | FFAR4MAPTHTTLMNAALDH1A1 | |
| SCHEMBL8627628 | 0.87 | FFAR4 (0.44) | FFAR4MAPTCYTH2TSHRCA12 | |
| SCHEMBL8759075 | 0.84 | MCL1 (0.41) | FFAR4HTTTSHRALDH1A1 | |
| SCHEMBL8632837 | 0.83 | LMNA (0.51) | FFAR4MAPTMEN1KMT2ACA12 | |
| SCHEMBL8631345 | 0.82 | MCL1 (0.49) | FFAR4MAPTHTTMEN1KMT2A | |
| SCHEMBL8630028 | 0.80 | ALDH1A1 (0.45) | FFAR4MAPTHTTMAPK1CYTH2 | |
| SCHEMBL8632286 | 0.78 | KIT (0.45) | MAPTMEN1KMT2ACA12CA1 | |
| SCHEMBL8628067 | 0.78 | SMN1; SMN2 (0.43) | FFAR4MAPTMEN1KMT2ACYTH2 | |
| SCHEMBL8628072 | 0.78 | ERBB2 (0.45) | MEN1KMT2AAVPR2GPR27ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |