Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | CYTH2 | Q99418 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | CCR4 | P51679 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8627985 | 0.87 | FFAR4 (0.50) | FFAR4CYTH2TSHRKDM4EALDH1A1 | |
| SCHEMBL8631496 | 0.85 | MAPK14 (0.43) | FFAR4CYTH2TSHRKDM4ERXFP1 | |
| SCHEMBL8629394 | 0.83 | KDM4E (0.40) | FFAR4KDM4EHSD17B10HPGDLMNA | |
| SCHEMBL8634775 | 0.83 | NAT1 (0.50) | KDM4EHSD17B10ALDH1A1HPGDLMNA | |
| SCHEMBL8632286 | 0.82 | KIT (0.45) | KDM4EHSD17B10ALDH1A1LMNAPKM | |
| SCHEMBL8632837 | 0.82 | LMNA (0.51) | FFAR4KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL8630028 | 0.82 | ALDH1A1 (0.45) | FFAR4CYTH2TSHRALDH1A1LMNA | |
| SCHEMBL8628067 | 0.80 | SMN1; SMN2 (0.43) | FFAR4CYTH2TSHRALDH1A1LMNA | |
| SCHEMBL8631345 | 0.79 | MCL1 (0.49) | FFAR4TSHRKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL8632810 | 0.79 | STAT3 (0.42) | FFAR4CYTH2TSHRALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |