Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.72 |
| ▸ | LMNA | P02545 | 2/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.72 |
| ▸ | PKM | P14618 | 2/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | CASP1 | P29466 | 1/20 | 0.60 |
| ▸ | CASP7 | P55210 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | CA1 | P00915 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | GRK2 | P25098 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL863168 | 0.88 | MEN1 (0.69) | ALDH1A1LMNASMN1; SMN2PKMKDM4E | |
| Acedapsone SCHEMBL152710 | 0.86 | PKM (0.85) | ALDH1A1SMN1; SMN2PKMCYP2C19KDM4E | |
| SCHEMBL68518 | 0.86 | POLB (0.74) | ALDH1A1HPGDTSHRPOLBCA1 | |
| Acedapsone SCHEMBL28716352 | 0.84 | PKM (0.82) | ALDH1A1SMN1; SMN2PKMCYP2C19KDM4E | |
| Acedapsone SCHEMBL22518385 | 0.84 | PKM (0.82) | ALDH1A1SMN1; SMN2PKMCYP2C19KDM4E | |
| SCHEMBL19398872 | 0.84 | ALDH1A1 (0.64) | ALDH1A1LMNASMN1; SMN2PKMKDM4E | |
| SCHEMBL17477152 | 0.83 | PKM (0.70) | ALDH1A1LMNAPKMCYP2C19KDM4E | |
| SCHEMBL14563219 | 0.83 | MEN1 (0.62) | ALDH1A1LMNASMN1; SMN2PKMKDM4E | |
| SCHEMBL6323372 | 0.83 | ALDH1A1 (0.68) | ALDH1A1LMNASMN1; SMN2PKMKDM4E | |
| SCHEMBL13728829 | 0.82 | IDO1 (0.71) | ALDH1A1LMNASMN1; SMN2PKMCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3180307-B1 | PROCESS FOR THE SYNTHESIS OF DAPSONE AND ITS INTERMEDIATES | SEEGPHARM SA (CH) | 2019-02-13 | — | — | EP | disclosed |
| US-9845289-B2 | Process for the synthesis of Dapsone and its intermediates | SEEGPHARM SA (CH) | 2017-12-19 | — | — | US | disclosed |
| US-20170217883-A1 | PROCESS FOR THE SYNTHESIS OF DAPSONE AND ITS INTERMEDIATES | SEEGPHARM SA (CH) | 2017-08-03 | — | — | US | disclosed |
| EP-3180307-A1 | PROCESS FOR THE SYNTHESIS OF DAPSONE AND ITS INTERMEDIATES | Seegpharm SA (CH) | 2017-06-21 | — | — | EP | disclosed |
| WO-2016016321-A1 | PROCESS FOR THE SYNTHESIS OF DAPSONE AND ITS INTERMEDIATES | SEEGPHARM SA (CH) | 2016-02-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170217883-A1 | PROCESS FOR THE SYNTHESIS OF DAPSONE AND ITS INTERMEDIATES | DHPS, FDPS, DAP3 | ALDH1A1 1853/4885LMNA 3385/4885SMN1; SMN2 4698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.