Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.58 |
| ▸ | CDK1 | P06493 | 1/20 | 0.50 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.50 |
| ▸ | GSK3A | P49840 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.50 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10693011 | 0.75 | CDK1 (0.50) | ACHECDK1CCNB1GSK3AGSK3B | |
| SCHEMBL8496004 | 0.71 | CDK1 (0.54) | ACHECDK1CCNB1GSK3AGSK3B | |
| SCHEMBL7221859 | 0.71 | KDM4E (0.80) | ACHEALDH1A1KDM4EMAPTGAA | |
| SCHEMBL8497298 | 0.70 | CDK1 (0.53) | ACHECDK1CCNB1GSK3AGSK3B | |
| SCHEMBL16552242 | 0.69 | TUBB4A (0.79) | ACHEALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL29729547 | 0.69 | TUBB4A (0.79) | ACHEALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL10689936 | 0.69 | ALDH1A1 (0.42) | ACHEALDH1A1KDM4EGAALMNA | |
| Machilin G SCHEMBL31108393 | 0.69 | MAPK9 (0.75) | ACHESOAT1 | |
| Machilin G SCHEMBL29477295 | 0.69 | MAPK9 (0.75) | ACHESOAT1 | |
| Machilin G SCHEMBL29477303 | 0.69 | MAPK9 (0.75) | ACHESOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0646570-B1 | PROCESS FOR PRODUCING LIGNAN COMPOUND | SHIONOGI & CO (JP) | 1998-06-24 | — | — | EP | disclosed |
| US-5488134-A | Preparation of compounds of lignan series | SHIONOGI & CO., LTD. (JP) | 1996-01-30 | — | — | US | disclosed |
| EP-0646570-A1 | PROCESS FOR PRODUCING LIGNAN COMPOUND | SHIONOGI & CO., LTD. (JP) | 1995-04-05 | — | — | EP | disclosed |