Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 8/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | GPX4 | P36969 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.35 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8634664 | 0.87 | GRM4 (0.46) | MAPTGRM4ALDH1A1KDM4EKMT2A | |
| SCHEMBL8632028 | 0.87 | GRM4 (0.41) | GRM4ALDH1A1KDM4EKMT2AHSD17B10 | |
| SCHEMBL4684908 | 0.76 | GRM4 (0.40) | MAPTGRM4ALDH1A1KDM4EKMT2A | |
| SCHEMBL8634000 | 0.74 | AVPR1A (0.41) | AVPR2AVPR1A | |
| SCHEMBL8632070 | 0.74 | GRM4 (0.40) | MAPTGRM4ALDH1A1KDM4EKMT2A | |
| SCHEMBL4684901 | 0.73 | AVPR2 (0.47) | GRM4AVPR2AVPR1ACHRM1 | |
| SCHEMBL8633396 | 0.72 | CHRM5 (0.41) | GRM4ALDH1A1KDM4EKMT2AHSD17B10 | |
| SCHEMBL8632058 | 0.72 | ALDH1A1 (0.43) | MAPTGRM4ALDH1A1KDM4EKMT2A | |
| SCHEMBL8627405 | 0.72 | GRM4 (0.41) | MAPTGRM4ALDH1A1KDM4EKMT2A | |
| SCHEMBL8628426 | 0.72 | LMNA (0.44) | MAPTGRM4ALDH1A1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753644-A | Vasopressin antagonist and oxytocin antagonist | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |