SCHEMBL8632124

SCHEMBL8632124

FC(F)(F)c1cc(Cl)c(Oc2cc(Cl)c(OCC=C(Cl)Cl)cc2Cl)c(Cl)c1

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MRGPRX4 Q96LA9 14/20 0.35
FFAR1 O14842 2/20 0.33
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8634035 0.88 MRGPRX4 (0.34) MRGPRX4FFAR1
SCHEMBL8900222 0.83 TDP1 (0.36) MRGPRX4FFAR1THRB
SCHEMBL8635385 0.82 CYP1A2 (0.51) FFAR1
SCHEMBL8634571 0.80 THRB (0.39) MRGPRX4FFAR1THRB
SCHEMBL8633882 0.80 RXRA (0.39) MRGPRX4FFAR1
SCHEMBL8631548 0.78 CYP1A2 (0.41) MRGPRX4FFAR1
SCHEMBL8637760 0.78 CYP1A2 (0.41) MRGPRX4FFAR1
SCHEMBL8633492 0.77 FFAR1 (0.47) MRGPRX4FFAR1
SCHEMBL8635064 0.76 CYP1A2 (0.47) FFAR1
SCHEMBL8633632 0.75 FFAR1 (0.51) MRGPRX4FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648729-B1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL CO (JP) 1998-07-15 EP disclosed
US-5698702-A INTERMEDIATES FOR INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-16 US disclosed
US-5530015-A Dihaloprene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient, and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-06-25 US disclosed
EP-0648729-A1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP disclosed