SCHEMBL8633882

SCHEMBL8633882

FC(F)(F)c1ccc(Oc2cc(Cl)c(OCC=C(Cl)Cl)cc2Cl)c(C(F)(F)F)c1

nearest known ligand 0.41

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
RXRA P19793 1/20 0.39
RXRB P28702 1/20 0.39
RXRG P48443 1/20 0.39
MRGPRX4 Q96LA9 14/20 0.38
FFAR1 O14842 2/20 0.37
PTGDR2 Q9Y5Y4 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8635428 0.89 RXRA (0.39) RXRARXRBRXRGMRGPRX4FFAR1
SCHEMBL8632792 0.83 RXRA (0.38) RXRARXRBRXRGMRGPRX4FFAR1
SCHEMBL8637760 0.81 CYP1A2 (0.41) MRGPRX4FFAR1
SCHEMBL8632124 0.80 MRGPRX4 (0.35) MRGPRX4FFAR1
SCHEMBL8633632 0.79 FFAR1 (0.51) MRGPRX4FFAR1
SCHEMBL8636474 0.78 RXRA (0.38) RXRARXRBRXRGFFAR1
SCHEMBL8634571 0.76 THRB (0.39) RXRARXRBRXRGMRGPRX4FFAR1
SCHEMBL8633492 0.76 FFAR1 (0.47) MRGPRX4FFAR1
SCHEMBL8635385 0.76 CYP1A2 (0.51) FFAR1
SCHEMBL8636562 0.75 HPGD (0.33) PTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648729-B1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL CO (JP) 1998-07-15 EP disclosed
US-5698702-A INTERMEDIATES FOR INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-16 US disclosed
US-5530015-A Dihaloprene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient, and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-06-25 US disclosed
EP-0648729-A1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP disclosed