SCHEMBL8633632

SCHEMBL8633632

FC(F)(F)c1ccc(Oc2ccc(OCC=C(Cl)Cl)c(Cl)c2)c(Cl)c1

nearest known ligand 0.58

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 3/20 0.51
MEN1 O00255 1/20 0.47
TTR P02766 1/20 0.47
PPOX P50336 1/20 0.47
KMT2A Q03164 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
HTR2A P28223 4/20 0.46
SLC6A4 P31645 4/20 0.46
KCNH2 Q12809 4/20 0.46
MRGPRX4 Q96LA9 9/20 0.43
PPARD Q03181 2/20 0.42
PPARA Q07869 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8634562 0.91 FFAR1 (0.47) FFAR1MEN1TTRPPOXKMT2A
SCHEMBL8632925 0.89 FFAR1 (0.50) FFAR1MEN1TTRPPOXKMT2A
SCHEMBL8633492 0.89 FFAR1 (0.47) FFAR1MEN1TTRPPOXKMT2A
SCHEMBL8651091 0.83 TDP1 (0.48) FFAR1TTRTDP1HTR2ASLC6A4
SCHEMBL8638413 0.81 FFAR1 (0.47) FFAR1MEN1TTRPPOXKMT2A
SCHEMBL8635057 0.81 RAB9A (0.45) FFAR1TDP1
SCHEMBL8993398 0.81 LMNA (0.47)
SCHEMBL8636194 0.80 SMN1; SMN2 (0.51) FFAR1TDP1
SCHEMBL8635410 0.80 HSP90AA1 (0.46) HTR2ASLC6A4KCNH2PPARA
SCHEMBL8634571 0.80 THRB (0.39) FFAR1MEN1TTRPPOXKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648729-B1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL CO (JP) 1998-07-15 EP disclosed
US-5698702-A INTERMEDIATES FOR INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-16 US disclosed
US-5530015-A Dihaloprene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient, and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-06-25 US disclosed
EP-0648729-A1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP disclosed