SCHEMBL8634571

SCHEMBL8634571

FC(F)(F)c1cc(Cl)c(Oc2ccc(OCC=C(Cl)Cl)c(C(F)(F)F)c2)c(Cl)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 4/20 0.39
THRA P10827 2/20 0.39
FFAR1 O14842 3/20 0.36
MRGPRX4 Q96LA9 2/20 0.35
HTR2A P28223 3/20 0.34
SLC6A4 P31645 3/20 0.34
KCNH2 Q12809 3/20 0.34
AR P10275 1/20 0.34
MEN1 O00255 1/20 0.34
TTR P02766 1/20 0.34
PPOX P50336 1/20 0.34
KMT2A Q03164 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
PPARD Q03181 1/20 0.34
RXRA P19793 1/20 0.33
RXRB P28702 1/20 0.33
RXRG P48443 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
RORC P51449 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8633636 0.90 THRB (0.36) THRBTHRAFFAR1MRGPRX4HTR2A
SCHEMBL8634961 0.87 RXRA (0.35) MRGPRX4ARPPARDRXRARXRB
SCHEMBL8636474 0.85 RXRA (0.38) THRBFFAR1HTR2ASLC6A4KCNH2
SCHEMBL8635269 0.84 RAB9A (0.53) FFAR1TDP1RAB9ASMN1; SMN2
SCHEMBL8633081 0.82 MAOB (0.43) THRBTHRAMRGPRX4ARRXRA
SCHEMBL8632792 0.81 RXRA (0.38) THRBTHRAFFAR1MRGPRX4HTR2A
SCHEMBL8634174 0.81 AR (0.39) MRGPRX4ARPPARD
SCHEMBL8632124 0.80 MRGPRX4 (0.35) THRBFFAR1MRGPRX4
SCHEMBL8632518 0.80 MAPT (0.39) ARPPARDRXRARXRBRXRG
SCHEMBL8633895 0.80 AR (0.51) FFAR1MRGPRX4HTR2ASLC6A4KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648729-B1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL CO (JP) 1998-07-15 EP disclosed
US-5698702-A INTERMEDIATES FOR INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-16 US disclosed
US-5530015-A Dihaloprene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient, and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-06-25 US disclosed
EP-0648729-A1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP disclosed