Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | TSPO | P30536 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL901479 | 0.77 | TSPO (0.55) | SIRT2SIRT1TSPO | |
| SCHEMBL8595169 | 0.72 | SIRT1 (0.50) | SIRT2SIRT1CASP1SIGMAR1 | |
| SCHEMBL3258128 | 0.71 | SIRT1 (0.63) | SIRT2SIRT1CASP1SIGMAR1 | |
| SCHEMBL11848642 | 0.68 | KDM4E (0.50) | SIRT2SIRT1KMT2A | |
| Sulfuric Acid SCHEMBL8592514 | 0.68 | SIRT1 (0.57) | SIRT2SIRT1CASP1 | |
| SCHEMBL11843108 | 0.68 | KDM4E (0.48) | — | |
| SCHEMBL11835576 | 0.66 | GABRA1 (0.44) | SIRT2SIRT1CASP1SIGMAR1 | |
| SCHEMBL11844570 | 0.66 | SIRT2 (0.43) | SIRT2SIRT1CASP1SIGMAR1KMT2A | |
| SCHEMBL8575677 | 0.65 | SIRT1 (0.46) | SIRT2SIRT1CASP1KMT2A | |
| SCHEMBL8632139 | 0.65 | ABCB1 (0.35) | SIRT2SIRT1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998018464-A1 | SUBSTITUTED TRICYCLICS | ELI LILLY AND COMPANY (US) | 1998-05-07 | — | — | WO | disclosed |