Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.35 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8630372 | 0.87 | USP2 (0.34) | KDM4EALDH1A1POLBKDM1AMEN1 | |
| SCHEMBL8630374 | 0.87 | USP2 (0.34) | KDM4EALDH1A1POLBKDM1AMEN1 | |
| Hydrochloric Acid SCHEMBL8629084 | 0.82 | CFD (0.38) | KDM4EALDH1A1POLBKDM1AMEN1 | |
| SCHEMBL8632827 | 0.78 | RIPK1 (0.36) | KDM4EALDH1A1KDM1AKMT2AMAPT | |
| SCHEMBL4893812 | 0.74 | ALDH1A1 (0.44) | TLR2ERN1TLR1TLR6KDM4E | |
| SCHEMBL8633026 | 0.73 | BACE1 (0.40) | — | |
| SCHEMBL9011882 | 0.72 | ALDH1A1 (0.43) | TLR2ERN1TLR1TLR6KDM4E | |
| SCHEMBL7392294 | 0.70 | MAOA (0.56) | KDM4EALDH1A1POLBRAB9AMEN1 | |
| SCHEMBL7429083 | 0.70 | SMYD2 (0.30) | — | |
| SCHEMBL7394096 | 0.69 | ALDH1A1 (0.33) | TLR2ERN1TLR1TLR6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811548-A | USEFUL AS RESEARCH TOOLS IN THE DETERMINATION OF BIOLOGICALLY ACTIVE PEPTIDE SEQUENCES | HOFFMANN-LA ROCHE INC. (US) | 1998-09-22 | — | — | US | disclosed |
| US-5811389-A | INHIBITING PLATELET AGGREGATION; BLOOD DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 1998-09-22 | — | — | US | disclosed |