Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | SORD | Q00796 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8633635 | 0.85 | TSHR (0.44) | HSD17B10TSHRROCK2ALDH1A1KDM4E | |
| SCHEMBL8700994 | 0.79 | AOC3 (0.41) | HSD17B10TSHRALDH1A1KMT2ANPC1 | |
| SCHEMBL8653967 | 0.79 | PDGFRB (0.51) | HSD17B10TSHRAKT1 | |
| SCHEMBL8633823 | 0.77 | NCF1 (0.39) | HSD17B10TSHRALDH1A1KDM4EKMT2A | |
| SCHEMBL8696288 | 0.76 | HSD17B10 (0.36) | HSD17B10TSHRALDH1A1KDM4EKMT2A | |
| SCHEMBL8634059 | 0.75 | ITGB3 (0.44) | HSD17B10TSHRROCK2ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL8699382 | 0.74 | ITGB3 (0.43) | HSD17B10TSHRROCK2ALDH1A1KDM4E | |
| SCHEMBL8700057 | 0.74 | NCF1 (0.59) | HSD17B10TSHRKDM4EKMT2AMAPK1 | |
| SCHEMBL8696260 | 0.72 | CYP2C9 (0.38) | HSD17B10TSHRROCK2ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL8631358 | 0.72 | CYP2C9 (0.38) | HSD17B10TSHRROCK2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753659-A | ANTICOAGULANTS FOR BLOOD DISORDER, CARDIOVASCULAR DISORDER, THROMBOSIS, | ZENECA LIMITED (GB) | 1998-05-19 | — | — | US | disclosed |
| US-5750754-A | TERTIARY BUTYL 3-METHYL-4-SUBSTITUTED BUTYRATE; CHEMICAL INTERMEDIATES FOR ANTICAOGULANT DRUGS | ZENECA LIMITED (GB) | 1998-05-12 | — | — | US | disclosed |