Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 2/20 | 0.32 |
| ▸ | TNKS | O95271 | 1/20 | 0.32 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.32 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8653967 | 0.82 | PDGFRB (0.51) | HSD17B10TSHRPDGFRB | |
| SCHEMBL8633635 | 0.76 | TSHR (0.44) | HSD17B10TSHRALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL8700994 | 0.76 | AOC3 (0.41) | HSD17B10TSHRALDH1A1KMT2AMEN1 | |
| SCHEMBL8633385 | 0.76 | HSD17B10 (0.43) | HSD17B10TSHRALDH1A1KDM4EKMT2A | |
| SCHEMBL8654154 | 0.74 | SLC27A1 (0.37) | HSD17B10TSHRALDH1A1KDM4ETDP1 | |
| SCHEMBL8700057 | 0.73 | NCF1 (0.59) | HSD17B10TSHRKDM4EKMT2AMEN1 | |
| SCHEMBL8654165 | 0.73 | PDGFRB (0.33) | HSD17B10TSHRPDGFRBALDH1A1KDM4E | |
| SCHEMBL8633823 | 0.72 | NCF1 (0.39) | HSD17B10TSHRALDH1A1KDM4EKMT2A | |
| SCHEMBL8634059 | 0.66 | ITGB3 (0.44) | HSD17B10TSHRALDH1A1KDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8699382 | 0.65 | ITGB3 (0.43) | HSD17B10TSHRALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750754-A | TERTIARY BUTYL 3-METHYL-4-SUBSTITUTED BUTYRATE; CHEMICAL INTERMEDIATES FOR ANTICAOGULANT DRUGS | ZENECA LIMITED (GB) | 1998-05-12 | — | — | US | disclosed |