Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 3/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8633823 | 0.88 | NCF1 (0.39) | TSHRHSD17B10ALDH1A1KMT2AMEN1 | |
| SCHEMBL8633635 | 0.86 | TSHR (0.44) | AOC3TSHRHSD17B10ALDH1A1MAPK1 | |
| SCHEMBL8653967 | 0.79 | PDGFRB (0.51) | TSHRHSD17B10 | |
| SCHEMBL8633385 | 0.79 | HSD17B10 (0.43) | TSHRHSD17B10ALDH1A1KMT2AMAPK1 | |
| SCHEMBL8700057 | 0.78 | NCF1 (0.59) | TSHRHSD17B10KMT2AMEN1MAPK1 | |
| SCHEMBL8633528 | 0.77 | AOC3 (0.39) | AOC3PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL8696288 | 0.76 | HSD17B10 (0.36) | TSHRHSD17B10ALDH1A1KMT2AMEN1 | |
| SCHEMBL8634059 | 0.75 | ITGB3 (0.44) | AOC3TSHRHSD17B10OPRM1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8699382 | 0.74 | ITGB3 (0.43) | AOC3TSHRHSD17B10OPRM1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8637477 | 0.74 | GAA (0.46) | AOC3TSHRHSD17B10OPRM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750754-A | TERTIARY BUTYL 3-METHYL-4-SUBSTITUTED BUTYRATE; CHEMICAL INTERMEDIATES FOR ANTICAOGULANT DRUGS | ZENECA LIMITED (GB) | 1998-05-12 | — | — | US | disclosed |