Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 3/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | PLAT | P00750 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8632788 | 0.88 | MAPT (0.37) | TSHRHSD17B10KMT2AALDH1A1NPSR1 | |
| SCHEMBL8633669 | 0.86 | CYP2C9 (0.44) | TSHRALDH1A1MAPK1MAPT | |
| SCHEMBL8631977 | 0.80 | ROCK2 (0.42) | AOC3TSHRKMT2AALDH1A1MAPK1 | |
| SCHEMBL8630734 | 0.78 | ROCK2 (0.52) | AOC3F10ALDH1A1NPC1MAPT | |
| SCHEMBL8649593 | 0.78 | NCF1 (0.58) | TSHRHSD17B10KMT2ANPSR1MAPK1 | |
| SCHEMBL8700994 | 0.77 | AOC3 (0.41) | AOC3PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL8634919 | 0.74 | CYP2C9 (0.37) | AOC3TSHRALDH1A1MAPK1NPC1 | |
| SCHEMBL8632221 | 0.72 | TSHR (0.40) | AOC3TSHRKMT2AF10ALDH1A1 | |
| SCHEMBL8632956 | 0.71 | CYP2C9 (0.38) | TSHRHSD17B10ALDH1A1NPSR1MAPK1 | |
| SCHEMBL8636239 | 0.70 | CHRM1 (0.39) | AOC3TSHRCHRM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753659-A | ANTICOAGULANTS FOR BLOOD DISORDER, CARDIOVASCULAR DISORDER, THROMBOSIS, | ZENECA LIMITED (GB) | 1998-05-19 | — | — | US | disclosed |
| US-5728701-A | INHIBIT PLATELET AGGREGATION | ZENECA LIMITED (GB) | 1998-03-17 | — | — | US | disclosed |