SCHEMBL8638413

SCHEMBL8638413

FC(F)(F)c1ccc(Oc2ccc(OCC=C(Br)Br)c(Br)c2)c(Cl)c1

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 5/20 0.47
MEN1 O00255 1/20 0.44
TTR P02766 1/20 0.44
PPOX P50336 1/20 0.44
KMT2A Q03164 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
SLC6A4 P31645 5/20 0.41
HTR2A P28223 4/20 0.41
KCNH2 Q12809 4/20 0.41
L3MBTL1 Q9Y468 2/20 0.38
MRGPRX4 Q96LA9 4/20 0.38
THRB P10828 1/20 0.37
LMNA P02545 1/20 0.37
MAPT P10636 1/20 0.37
ATM Q13315 1/20 0.37
PPARD Q03181 1/20 0.37
PPARA Q07869 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8632925 0.92 FFAR1 (0.50) FFAR1MEN1TTRPPOXKMT2A
SCHEMBL8634562 0.91 FFAR1 (0.47) FFAR1MEN1TTRPPOXKMT2A
SCHEMBL8633939 0.86 RAB9A (0.53) FFAR1MEN1KMT2ATDP1LMNA
SCHEMBL8633870 0.84 SMN1; SMN2 (0.53) FFAR1MEN1KMT2ATDP1LMNA
SCHEMBL8633632 0.81 FFAR1 (0.51) FFAR1MEN1TTRPPOXKMT2A
SCHEMBL8637045 0.80 PKM (0.37) TDP1L3MBTL1LMNAMAPT
SCHEMBL8634563 0.79 SMN1; SMN2 (0.49) FFAR1MEN1KMT2AL3MBTL1LMNA
SCHEMBL8634835 0.79 THRB (0.42) FFAR1SLC6A4L3MBTL1THRBLMNA
SCHEMBL8636962 0.78 SMN1; SMN2 (0.50) FFAR1MEN1KMT2ATDP1LMNA
SCHEMBL8633636 0.77 THRB (0.36) FFAR1MEN1TTRPPOXKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648729-B1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL CO (JP) 1998-07-15 EP disclosed
US-5698702-A INTERMEDIATES FOR INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-16 US disclosed
US-5530015-A Dihaloprene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient, and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-06-25 US disclosed
EP-0648729-A1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP disclosed