Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 15/20 | 0.38 |
| ▸ | RARG | P13631 | 15/20 | 0.38 |
| ▸ | RARA | P10276 | 13/20 | 0.38 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CRABP2 | P29373 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HNF4A | P41235 | 1/20 | 0.32 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8666520 | 0.92 | RARB (0.38) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL8604136 | 0.85 | RARB (0.53) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL8605671 | 0.77 | RARB (0.43) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL8605739 | 0.76 | RARB (0.53) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL8633713 | 0.74 | RARB (0.33) | RARBRARGRARA | |
| SCHEMBL8580705 | 0.73 | RARB (0.65) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL8605748 | 0.69 | RARB (0.45) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL8772690 | 0.68 | RARB (0.45) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL8772747 | 0.67 | RARA (0.50) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL8772626 | 0.66 | RARA (0.62) | RARBRARGRARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825986-A1 | QUINOLYL-ETHYNYL DERIVATIVES HAVING RETINOID-LIKE ACTIVITY | Allergan (US) | 1998-03-04 | — | — | EP | disclosed |
| WO-1996036609-A1 | QUINOLYL-ETHYNYL DERIVATIVES HAVING RETINOID-LIKE ACTIVITY | ALLERGAN (US) | 1996-11-21 | — | — | WO | disclosed |