Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | SHBG | P04278 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL456782 | 0.85 | GABRA1 (0.52) | GABRA1GABRB2HSPA5SIGMAR1MEN1 | |
| SCHEMBL8630814 | 0.85 | PTGS2 (0.36) | GABRA1GABRB2HSPA5MEN1KMT2A | |
| SCHEMBL3593411 | 0.79 | GABRA1 (0.41) | GABRA1GABRB2HSPA5MEN1KMT2A | |
| SCHEMBL20804437 | 0.76 | PTGS2 (0.30) | PTGS2RAPGEF4 | |
| SCHEMBL31092543 | 0.73 | SHBG (0.55) | GABRA1GABRB2HSPA5MEN1GAA | |
| SCHEMBL1022721 | 0.73 | SHBG (0.55) | GABRA1GABRB2HSPA5MEN1GAA | |
| SCHEMBL9853387 | 0.73 | ALDH1A1 (0.50) | HSPA5MEN1GAAKMT2ANOS3 | |
| SCHEMBL8631935 | 0.73 | HSPA5 (0.33) | HSPA5MEN1GAAKMT2ANOS3 | |
| SCHEMBL2494357 | 0.73 | GABRA1 (0.39) | GABRA1GABRB2NOS3NOS1NOS2 | |
| SCHEMBL2228767 | 0.72 | HSPA5 (0.39) | HSPA5MEN1GAAKMT2ANOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101238173-A | Flame retarded styrenic foams and foam precursors | ALBEMARLE CORP (US) | 2008-08-06 | — | — | CN | disclosed |
| EP-0718291-B1 | Method for the preparation of triazole compounds | CHUGAI PHARMACEUTICAL CO LTD (JP) | 1998-07-08 | — | — | EP | disclosed |
| US-5567825-A | Method for the preparation of a triazole compound | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1996-10-22 | — | — | US | disclosed |
| EP-0718291-A1 | Method for the preparation of triazole compounds | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1996-06-26 | — | — | EP | disclosed |
| US-4759915-A | Solvent extraction using solvent containing mixture of trialkyl amines with triisooctyl amine and alkyl benzene; stripping with ammonium hydroxide, and separation | GTE PRODUCTS CORPORATION (US) | 1988-07-26 | — | — | US | disclosed |