SCHEMBL8633855

SCHEMBL8633855

Oc1nc(O)nc(N(Cc2ccccc2)Cc2ccccc2)n1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.42
MGLL Q99685 3/20 0.41
CYP2C19 P33261 1/20 0.41
OPRK1 P41145 3/20 0.40
ALDH1A1 P00352 2/20 0.40
CHRM2 P08172 1/20 0.40
ADRA2A P08913 1/20 0.40
ADRA2B P18089 1/20 0.40
ADRA2C P18825 1/20 0.40
DRD1 P21728 1/20 0.40
SLC6A2 P23975 1/20 0.40
HTR2A P28223 1/20 0.40
SLC6A4 P31645 1/20 0.40
ADRA1A P35348 1/20 0.40
HRH1 P35367 1/20 0.40
SLC6A3 Q01959 1/20 0.40
KCNH2 Q12809 1/20 0.40
HCAR3 P49019 1/20 0.39
KDM4E B2RXH2 1/20 0.39
LMNA P02545 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3393676 0.76 TSHR (0.42) TSHRMGLLCYP2C19OPRK1ALDH1A1
SCHEMBL11292840 0.76 MAPT (0.50) TSHRCYP2C19ALDH1A1SMN1; SMN2AOC3
SCHEMBL15495564 0.72 ESR1 (0.44) CYP2C19ALDH1A1ADRA2ASLC6A2KDM4E
SCHEMBL11668680 0.72 GAA (0.50) TSHRCYP2C19ALDH1A1KDM4ELMNA
SCHEMBL6723521 0.72 KCNH3 (0.54) ALDH1A1KDM4ELMNA
SCHEMBL11402745 0.68 ALDH1A1 (0.51) TSHRCYP2C19ALDH1A1SMN1; SMN2CRHR1
SCHEMBL31107306 0.68 ALDH1A1 (0.44) TSHRMGLLCYP2C19ALDH1A1LMNA
SCHEMBL20844355 0.68 MAPT (0.63) TSHRCYP2C19SMN1; SMN2CRHR1AOC3
SCHEMBL29957104 0.67 CXCR1 (0.52) TSHRMGLLCYP2C19OPRK1ALDH1A1
SCHEMBL22118149 0.67 TSHR (0.47) TSHRMGLLCYP2C19ALDH1A1NR1H2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-10298167-A None JP disclosed
JP-H10298167-A TRIAZINE-BASED COMPOUND AND TONER FOR ELECTROPHOTOGRAPHY CONTAINING THE SAME COMPOUND NIPPON KAYAKU CO LTD 1998-11-10 JP disclosed