Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.37 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.37 |
| ▸ | HRH1 | P35367 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11292840 | 0.76 | MAPT (0.50) | TSHRCYP2C19ALDH1A1AOC3CYP2D6 | |
| SCHEMBL8633855 | 0.76 | TSHR (0.42) | TSHRCYP2C19ALDH1A1CRHR1AOC3 | |
| SCHEMBL6723521 | 0.72 | KCNH3 (0.54) | ALDH1A1LMNAKMT2AL3MBTL1GAA | |
| SCHEMBL11668680 | 0.72 | GAA (0.50) | TSHRCYP2C19ALDH1A1CRHR1AOC3 | |
| SCHEMBL11402745 | 0.68 | ALDH1A1 (0.51) | TSHRCYP2C19ALDH1A1CRHR1AOC3 | |
| SCHEMBL20844355 | 0.68 | MAPT (0.63) | TSHRCYP2C19CRHR1AOC3PDE4D | |
| SCHEMBL8422447 | 0.67 | CYP2C19 (0.53) | TSHRCYP2C19ALDH1A1CRHR1AOC3 | |
| SCHEMBL2960872 | 0.66 | CYP2C19 (0.78) | TSHRCYP2C19ALDH1A1AOC3MGLL | |
| SCHEMBL43183 | 0.66 | TSHR (0.74) | TSHRCYP2C19ALDH1A1AOC3LMNA | |
| SCHEMBL7148219 | 0.66 | TSHR (0.54) | TSHRCYP2C19ALDH1A1AOC3MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1394153-B1 | THIOL COMPOUND DERIVATIVES, HARDENING COMPOSITIONS CONTAINING THESE DERIVATIVES AND MOLDED ARTICLES THEREOF | UNIMATEC CO LTD (JP) | 2010-12-29 | — | — | EP | disclosed |
| US-7812157-B2 | Thiol compound derivative, curable composition containing the derivative, and molded product thereof | UNIMATEC CO., LTD. (JP) | 2010-10-12 | — | — | US | disclosed |
| US-20080227977-A1 | Thiol compound derivative, curable composition containing the derivative, and molded product thereof | UNIMATEC CO., LTD. | 2008-09-18 | — | — | US | disclosed |
| US-7384995-B2 | Thiol compound derivative, curable composition containing the derivative, and molded product thereof | UNIMATEC CO., LTD. (JP) | 2008-06-10 | — | — | US | disclosed |
| US-20070155868-A1 | Thiol compound derivative, curable composition containing the derivative, and molded product thereof | UNIMATEC CO., LTD. | 2007-07-05 | — | — | US | disclosed |
| US-7199169-B2 | Thiol compound derivative, hardening compositions containing these derivatives and molded articles thereof | UNIMATEC CO., LTD. (JP) | 2007-04-03 | — | — | US | disclosed |
| US-20040162368-A1 | Thiol compound derivative, hardening compositions containing these derivatives and molded articles thereof | UNIMATEC CO., LTD. (JP) | 2004-08-19 | — | — | US | disclosed |
| EP-1394153-A1 | THIOL COMPOUND DERIVATIVES, HARDENING COMPOSITIONS CONTAINING THESE DERIVATIVES AND MOLDED ARTICLES THEREOF | Unimatec Co., Ltd. (JP) | 2004-03-03 | — | — | EP | disclosed |
| US-4105627-A | MERCAPTOHETEROCYCLIC RESIN STABILIZERS | ARGUS CHEMICAL CORPORATION (US) | 1978-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080227977-A1 | Thiol compound derivative, curable composition containing the derivative, and molded product thereof | TST, CTH, NACA | TSHR 3849/4885CYP2C19 881/4885ALDH1A1 577/4885 |
| US-20040162368-A1 | Thiol compound derivative, hardening compositions containing these derivatives and molded articles thereof | TST, NACA, CTH | TSHR 4349/4885CYP2C19 1520/4885ALDH1A1 188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.