Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.46 |
| ▸ | F10 | P00742 | 2/20 | 0.45 |
| ▸ | HRH1 | P35367 | 2/20 | 0.45 |
| ▸ | CCR3 | P51677 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | LSS | P48449 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7961307 | 0.83 | F10 (0.52) | HRH3F10HRH1 | |
| SCHEMBL7399643 | 0.83 | HRH1 (0.57) | ITGB3ITGA2BHRH3HRH1CCR3 | |
| SCHEMBL7398480 | 0.73 | ITGB3 (0.53) | ITGB3ITGA2BHRH3F10HRH1 | |
| SCHEMBL8633871 | 0.72 | CYP2C9 (0.53) | ITGB3ITGA2BHRH3F10FFAR4 | |
| SCHEMBL7399619 | 0.71 | ITGB3 (0.51) | ITGB3ITGA2BHRH3HRH1CCR3 | |
| SCHEMBL7401896 | 0.71 | HRH3 (0.62) | ITGB3ITGA2BHRH3SMN1; SMN2LSS | |
| SCHEMBL7961303 | 0.71 | F10 (0.54) | HRH3F10HRH1FFAR4 | |
| SCHEMBL7332909 | 0.71 | ACACB (0.47) | ITGB3ITGA2BHRH3F10HRH1 | |
| SCHEMBL7955317 | 0.70 | HRH1 (0.47) | HRH3HRH1FFAR4 | |
| SCHEMBL4375414 | 0.70 | TSHR (0.70) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753659-A | ANTICOAGULANTS FOR BLOOD DISORDER, CARDIOVASCULAR DISORDER, THROMBOSIS, | ZENECA LIMITED (GB) | 1998-05-19 | — | — | US | disclosed |
| US-5750754-A | TERTIARY BUTYL 3-METHYL-4-SUBSTITUTED BUTYRATE; CHEMICAL INTERMEDIATES FOR ANTICAOGULANT DRUGS | ZENECA LIMITED (GB) | 1998-05-12 | — | — | US | disclosed |
| US-5728701-A | INHIBIT PLATELET AGGREGATION | ZENECA LIMITED (GB) | 1998-03-17 | — | — | US | disclosed |