Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 6/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | NCF1 | P14598 | 1/20 | 0.34 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8637013 | 0.83 | ITGB3 (0.38) | ITGB3ITGA2BALDH1A1MEN1CYP3A4 | |
| SCHEMBL7396531 | 0.71 | ITGB3 (0.49) | ITGB3ITGA2BMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8838053 | 0.68 | ADRB2 (0.39) | ITGB3ITGA2BCYP3A4CYP2C9ADRB2 | |
| Hydrochloric Acid SCHEMBL8838137 | 0.66 | DPP4 (0.48) | ITGB3ITGA2BNPSR1F10ADRB2 | |
| SCHEMBL8701209 | 0.66 | L3MBTL1 (0.37) | ITGB3ITGA2BMEN1KMT2AF10 | |
| SCHEMBL8699754 | 0.65 | L3MBTL1 (0.36) | ITGB3ITGA2BMEN1KMT2AF10 | |
| SCHEMBL8633916 | 0.65 | ADRB2 (0.35) | ITGB3ITGA2BF10ADRB2NCF1 | |
| SCHEMBL8838149 | 0.64 | ITGB3 (0.39) | ITGB3ITGA2BCYP3A4CYP2C9ADRB2 | |
| SCHEMBL8778807 | 0.64 | KMT2A (0.44) | ITGB3ITGA2BALDH1A1MEN1KMT2A | |
| SCHEMBL8837930 | 0.64 | SPHK1 (0.39) | ITGB3ITGA2BADRB2NCF1PLD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753659-A | ANTICOAGULANTS FOR BLOOD DISORDER, CARDIOVASCULAR DISORDER, THROMBOSIS, | ZENECA LIMITED (GB) | 1998-05-19 | — | — | US | disclosed |