Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | FLT4 | P35916 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | S100A9 | P06702 | 1/20 | 0.39 |
| ▸ | FBP1 | P09467 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8628709 | 0.91 | ERBB2 (0.40) | ERBB2HSP90AA1HSP90AB1MEN1KMT2A | |
| SCHEMBL8635286 | 0.89 | NAT1 (0.44) | MEN1KMT2ATDP1KDRS100A9 | |
| SCHEMBL8632682 | 0.84 | KDM1A (0.46) | MEN1KMT2ANPSR1POLBKDM4E | |
| SCHEMBL8634847 | 0.83 | NAT1 (0.46) | MEN1KMT2APGRMAPTLMNA | |
| SCHEMBL8759028 | 0.82 | PKM (0.39) | MEN1KMT2ATDP1PTGES2POLB | |
| SCHEMBL8631571 | 0.81 | KMO (0.47) | MEN1KMT2ATDP1PTGES2S100A9 | |
| SCHEMBL8633920 | 0.80 | FFAR4 (0.44) | MEN1KMT2ATDP1MAPTMAPK1 | |
| SCHEMBL8629976 | 0.80 | L3MBTL1 (0.51) | MEN1KMT2ANPSR1KDM4ERXFP1 | |
| SCHEMBL8630116 | 0.80 | MAPT (0.39) | MEN1KMT2ATDP1NPSR1POLB | |
| SCHEMBL8629936 | 0.80 | MAPK14 (0.42) | MEN1KMT2ATDP1RXFP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |