SCHEMBL8633959

SCHEMBL8633959

CC(C)(C)c1ccc(Oc2ccc(OCC=C(Br)Br)c(C(F)(F)F)c2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.39
HPGD P15428 2/20 0.39
RAB9A P51151 2/20 0.39
NPC1 O15118 1/20 0.39
ALDH1A1 P00352 1/20 0.39
MAPK1 P28482 1/20 0.39
MAOB P27338 1/20 0.37
AOC3 Q16853 1/20 0.37
SLC6A4 P31645 1/20 0.37
LMNA P02545 1/20 0.36
ATM Q13315 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
AR P10275 3/20 0.34
RECQL P46063 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
FGFR2 P21802 1/20 0.34
RXRA P19793 1/20 0.34
RXRB P28702 1/20 0.34
RXRG P48443 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8638939 0.91 SLC6A4 (0.41) MAPTRAB9AMAOBAOC3SLC6A4
SCHEMBL8632751 0.90 FFAR1 (0.37) ALDH1A1MAOBAOC3L3MBTL1AR
SCHEMBL8635907 0.90 MAPT (0.45) MAPTRAB9ANPC1ALDH1A1MAPK1
SCHEMBL8635187 0.89 SMN1; SMN2 (0.40) MAPTRAB9ANPC1ALDH1A1MAPK1
SCHEMBL8632518 0.88 MAPT (0.39) MAPTHPGDRAB9ANPC1ALDH1A1
SCHEMBL8637887 0.88 L3MBTL1 (0.39) MAPTRAB9AALDH1A1LMNAATM
SCHEMBL8638264 0.87 LMNA (0.44) MAPTMAOBLMNAATML3MBTL1
SCHEMBL8635708 0.86 AR (0.39) MAOBAOC3ARPPARGALOX5
SCHEMBL8635270 0.85 RXRA (0.35) MAPTMAOBAOC3SLC6A4LMNA
SCHEMBL8632656 0.85 KDM4E (0.37) RAB9AALDH1A1MAPK1LMNAAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648729-B1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL CO (JP) 1998-07-15 EP disclosed
US-5698702-A INTERMEDIATES FOR INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-16 US disclosed
US-5530015-A Dihaloprene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient, and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-06-25 US disclosed
EP-0648729-A1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP disclosed