Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.35 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8633381 | 0.88 | ALDH1A1 (0.39) | ALDH1A1AVPR2AVPR1AKCNK3MEN1 | |
| SCHEMBL4682740 | 0.85 | ALDH1A1 (0.43) | WDR5MAPTALDH1A1SMN1; SMN2AVPR2 | |
| SCHEMBL7344728 | 0.77 | ALDH1A1 (0.40) | WDR5MAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7336618 | 0.74 | PKM (0.42) | WDR5MAPTALDH1A1SMN1; SMN2AVPR2 | |
| SCHEMBL4697134 | 0.73 | ALDH1A1 (0.46) | ALDH1A1AVPR2AVPR1AKCNK3GAA | |
| SCHEMBL4684984 | 0.72 | AVPR2 (0.49) | WDR5MAPTALDH1A1SMN1; SMN2AVPR2 | |
| SCHEMBL4686745 | 0.71 | ALDH1A1 (0.41) | WDR5MAPTALDH1A1SMN1; SMN2AVPR2 | |
| SCHEMBL4684773 | 0.71 | AVPR2 (0.46) | WDR5MAPTALDH1A1SMN1; SMN2AVPR2 | |
| SCHEMBL8634401 | 0.70 | MAPT (0.36) | WDR5MAPTALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL7333794 | 0.70 | ALDH1A1 (0.41) | WDR5MAPTALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753644-A | Vasopressin antagonist and oxytocin antagonist | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |