Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | WDR5 | P61964 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8631703 | 0.89 | KCNK3 (0.33) | ALDH1A1KCNK3GAAALOX5P2RX7 | |
| SCHEMBL4682740 | 0.73 | ALDH1A1 (0.43) | MAPTWDR5ALDH1A1SMN1; SMN2P2RX7 | |
| SCHEMBL8634397 | 0.70 | WDR5 (0.41) | MAPTNPC1WDR5ALDH1A1SMN1; SMN2 | |
| SCHEMBL7344728 | 0.65 | ALDH1A1 (0.40) | MAPTWDR5ALDH1A1SMN1; SMN2 | |
| SCHEMBL7336618 | 0.64 | PKM (0.42) | MAPTNPC1WDR5ALDH1A1SMN1; SMN2 | |
| SCHEMBL9727483 | 0.63 | GAA (0.45) | ALDH1A1KCNK3GAANPSR1FPR2 | |
| SCHEMBL14256154 | 0.61 | HCRTR2 (0.35) | — | |
| SCHEMBL15962162 | 0.61 | MAPT (0.52) | MAPTNPC1ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL6173457 | 0.61 | MAPT (0.52) | MAPTNPC1ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL4697134 | 0.61 | ALDH1A1 (0.46) | ALDH1A1KCNK3GAAP2RX7SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753644-A | Vasopressin antagonist and oxytocin antagonist | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |