Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8629786 | 0.88 | KDM4E (0.45) | ALDH1A1KDM4ELMNAMAPTHTT | |
| SCHEMBL5140898 | 0.78 | CYP1A2 (0.48) | ALDH1A1KDM4ELMNANPC1RAB9A | |
| SCHEMBL5862781 | 0.78 | ALDH1A1 (0.47) | ALDH1A1KDM4ELMNAMAPTNPC1 | |
| SCHEMBL7810409 | 0.76 | ALDH1A1 (0.45) | ALDH1A1KDM4ELMNANPC1RAB9A | |
| SCHEMBL8634964 | 0.74 | NAMPT (0.46) | ALDH1A1KDM4ELMNAMAPTGAA | |
| SCHEMBL8631399 | 0.73 | LMNA (0.45) | ALDH1A1LMNAMAPTNPC1RAB9A | |
| SCHEMBL9226679 | 0.73 | SMN1; SMN2 (0.43) | ALDH1A1KDM4ELMNANPC1RAB9A | |
| SCHEMBL11168807 | 0.72 | POLB (0.42) | ALDH1A1KDM4ELMNAMAPTNPC1 | |
| SCHEMBL5862688 | 0.72 | SMN1; SMN2 (0.53) | ALDH1A1KDM4ELMNAMAPTHTT | |
| SCHEMBL5861519 | 0.72 | TRPM8 (0.47) | ALDH1A1KDM4ELMNAMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773465-A | Tartronic acids, their acetalic ethers and o-esters | DOMPE FARMACEUTICI S.P.A. (IT) | 1998-06-30 | — | — | US | disclosed |
| US-5656656-A | Tartronic acids, their acetalic ethers and O-esters | DOMPE FARMACEUTICI S.P.A. (IT) | 1997-08-12 | — | — | US | disclosed |
| EP-0667850-B1 | TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS | DOMPE FARMACEUTICI SPA (IT) | 1997-05-28 | — | — | EP | disclosed |
| WO-1994010127-A1 | TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS | DOMPE' FARMACEUTICI S.P.A. (IT) | 1994-05-11 | — | — | WO | disclosed |