Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 4/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8632213 | 0.89 | SLC2A1 (0.43) | KDM4EGAAMAPTCHRM1SLC2A1 | |
| SCHEMBL8635651 | 0.87 | ALDH1A1 (0.46) | KDM4EGAAMAPTCHRM1CYP2C9 | |
| SCHEMBL8633634 | 0.86 | CYP2C9 (0.46) | KDM4EGAAMAPTCYP2C9TSHR | |
| SCHEMBL8631971 | 0.81 | ITGB3 (0.40) | KDM4EGAAMAPTSLC2A1CYP2C9 | |
| SCHEMBL8636233 | 0.80 | CHRM1 (0.39) | KDM4EGAAMAPTCHRM1SLC2A1 | |
| SCHEMBL8634772 | 0.79 | GAA (0.39) | KDM4EGAAMAPTCYP2C9TSHR | |
| SCHEMBL8635770 | 0.78 | ROCK2 (0.49) | GAAMAPTCYP2C9TSHRALDH1A1 | |
| SCHEMBL8635264 | 0.77 | CYP2C9 (0.44) | KDM4EGAAMAPTCYP2C9TSHR | |
| SCHEMBL8632705 | 0.76 | CYP2C9 (0.42) | KDM4EGAAMAPTCYP2C9TSHR | |
| SCHEMBL8633523 | 0.75 | AOC3 (0.38) | MAPTCHRM1ALDH1A1MAPK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753659-A | ANTICOAGULANTS FOR BLOOD DISORDER, CARDIOVASCULAR DISORDER, THROMBOSIS, | ZENECA LIMITED (GB) | 1998-05-19 | — | — | US | disclosed |
| US-5750754-A | TERTIARY BUTYL 3-METHYL-4-SUBSTITUTED BUTYRATE; CHEMICAL INTERMEDIATES FOR ANTICAOGULANT DRUGS | ZENECA LIMITED (GB) | 1998-05-12 | — | — | US | disclosed |
| US-5728701-A | INHIBIT PLATELET AGGREGATION | ZENECA LIMITED (GB) | 1998-03-17 | — | — | US | disclosed |