Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | AVPR2 | P30518 | 5/20 | 0.34 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8634459 | 0.88 | CHRM5 (0.40) | HSD17B10CHRM5CHRM1CHRM3GRM4 | |
| SCHEMBL8635111 | 0.87 | CHRM5 (0.41) | HSD17B10CHRM5CHRM1CHRM3GRM4 | |
| SCHEMBL4684848 | 0.75 | AVPR2 (0.45) | HSD17B10CHRM5CHRM1CHRM3GRM4 | |
| SCHEMBL8901086 | 0.72 | CHRM1 (0.40) | HSD17B10CHRM5CHRM1CHRM3GRM4 | |
| SCHEMBL8631926 | 0.71 | AVPR2 (0.44) | HSD17B10CHRM5CHRM1CHRM3GRM4 | |
| SCHEMBL8900831 | 0.70 | CHRM1 (0.42) | HSD17B10CHRM5CHRM1CHRM3GRM4 | |
| SCHEMBL8633396 | 0.70 | CHRM5 (0.41) | HSD17B10CHRM5CHRM1CHRM3GRM4 | |
| SCHEMBL8632058 | 0.70 | ALDH1A1 (0.43) | HSD17B10CHRM5CHRM1CHRM3GRM4 | |
| SCHEMBL8632028 | 0.70 | GRM4 (0.41) | HSD17B10CHRM5CHRM1CHRM3GRM4 | |
| SCHEMBL8628426 | 0.70 | LMNA (0.44) | HSD17B10CHRM5CHRM1CHRM3GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753644-A | Vasopressin antagonist and oxytocin antagonist | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |