Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.41 |
| ▸ | TNKS | O95271 | 1/20 | 0.39 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | HTR7 | P34969 | 2/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 2/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.36 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8637686 | 0.88 | PTPRC (0.49) | PTPRCPTPN1HRH3PARP1PARP2 | |
| SCHEMBL8634486 | 0.83 | OPRD1 (0.47) | PTPRCPTPN1HRH3PARP1PARP2 | |
| SCHEMBL8633556 | 0.80 | HSD17B1 (0.60) | PTPRCPTPN1HRH3PARP1PARP2 | |
| SCHEMBL7510849 | 0.78 | PTPRC (0.48) | PTPRCPTPN1HRH3PARP1PARP2 | |
| SCHEMBL8635876 | 0.77 | HSD17B1 (0.56) | PTPRCPTPN1HRH3PARP1PARP2 | |
| SCHEMBL8072264 | 0.77 | HRH3 (0.54) | PTPRCPTPN1HRH3PARP1PARP2 | |
| SCHEMBL8634558 | 0.74 | PTPRC (0.46) | PTPRCPTPN1HRH3PARP1PARP2 | |
| SCHEMBL8635928 | 0.74 | PARP1 (0.48) | PTPRCPTPN1HRH3PARP1PARP2 | |
| SCHEMBL8633644 | 0.74 | PTPRC (0.46) | PTPRCPTPN1HRH3PARP1PARP2 | |
| SCHEMBL8631353 | 0.71 | PTPRC (0.56) | PTPRCPTPN1HRH3PARP1PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0601191-B1 | NOVEL TETRACYCLIC COMPOUND | KYOWA HAKKO KOGYO KK (JP) | 1998-07-22 | — | — | EP | disclosed |
| US-5371225-A | Immunosuppressants | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1994-12-06 | — | — | US | disclosed |
| EP-0601191-A1 | NOVEL TETRACYCLIC COMPOUND | KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) | 1994-06-15 | — | — | EP | disclosed |