Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | FGB | P02675 | 1/20 | 0.33 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8629520 | 0.85 | ACHE (0.44) | ALDH1A1LMNAMAPTAGTR1CYP1A2 | |
| SCHEMBL8683323 | 0.76 | KDM4E (0.43) | ALDH1A1LMNAKDM4ECYP1A2MEN1 | |
| SCHEMBL8629437 | 0.75 | BRD4 (0.45) | MAPK1ACHEMEN1KMT2ACTSA | |
| SCHEMBL7122164 | 0.74 | CA1 (0.50) | ALDH1A1LMNAMAPTALOX15MAPK1 | |
| SCHEMBL2593085 | 0.72 | SLC6A3 (0.44) | ALDH1A1LMNAKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL9025658 | 0.71 | IDO1 (0.38) | LMNAMAPTKDM4EACHEP2RX7 | |
| SCHEMBL8633347 | 0.70 | TSHR (0.44) | ALDH1A1MAPTHSD17B10KDM4EHPGD | |
| SCHEMBL9026742 | 0.70 | ATM (0.38) | KDM4EKMT2AP2RX7 | |
| SCHEMBL8629570 | 0.70 | GAA (0.44) | GAAALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL8630297 | 0.70 | PFKFB3 (0.38) | ALDH1A1KDM4ECYP3A4CASP1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5712299-A | TREATMENT OF NEURODEGENERATIVE DISORDERS | ASTRA AKTIEBOLAG (SE) | 1998-01-27 | — | — | US | disclosed |
| EP-0707574-A1 | NOVEL (1-PHENYL-1-HETEROCYCLYL)METHANOL AND (1-PHENYL-1-HETEROCYCLYL)METHYLAMINE DERIVATIVES | Astra Aktiebolag (SE) | 1996-04-24 | — | — | EP | disclosed |
| WO-1995001968-A1 | NOVEL (1-PHENYL-1-HETEROCYCLYL)METHANOL AND (1-PHENYL-1-HETEROCYCLYL)METHYLAMINE DERIVATIVES | ASTRA AKTIEBOLAG (SE) | 1995-01-19 | — | — | WO | disclosed |