SCHEMBL8635499

SCHEMBL8635499

CC(C)Oc1cccc(Oc2ccc(OCC=C(Cl)Cl)c(C(F)(F)F)c2)c1

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 3/20 0.43
RXRA P19793 1/20 0.37
RXRB P28702 1/20 0.37
RXRG P48443 1/20 0.37
CETP P11597 1/20 0.37
PPARD Q03181 2/20 0.36
PPARA Q07869 2/20 0.36
PPARG P37231 1/20 0.36
AR P10275 2/20 0.35
HTT P42858 1/20 0.34
KDM4E B2RXH2 1/20 0.34
NSD2 O96028 1/20 0.34
ALDH1A1 P00352 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
MRGPRX4 Q96LA9 3/20 0.34
PTPN5 P54829 1/20 0.33
CDK8 P49336 1/20 0.33
SUCNR1 Q9BXA5 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8634403 0.92 FFAR4 (0.43) FFAR4RXRARXRBRXRGCETP
SCHEMBL8636395 0.89 FFAR4 (0.39) FFAR4RXRARXRBRXRGCETP
SCHEMBL8635779 0.89 AR (0.39) PPARDPPARAARHTTALDH1A1
SCHEMBL8633011 0.88 MAPT (0.43) ARKDM4EALDH1A1SMN1; SMN2
SCHEMBL8638861 0.88 AR (0.38) PPARDPPARAPPARGARKDM4E
SCHEMBL8636591 0.87 MAPK1 (0.43) RXRARXRBRXRGCETPAR
SCHEMBL8634174 0.85 AR (0.39) FFAR4PPARDPPARAPPARGAR
SCHEMBL8633895 0.84 AR (0.51) PPARDPPARAPPARGARMRGPRX4
SCHEMBL8633081 0.84 MAOB (0.43) RXRARXRBRXRGARKDM4E
SCHEMBL8638742 0.83 FFAR1 (0.37) CETPPPARDPPARAPPARGAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648729-B1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL CO (JP) 1998-07-15 EP disclosed
US-5698702-A INTERMEDIATES FOR INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-16 US disclosed
US-5530015-A Dihaloprene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient, and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-06-25 US disclosed
EP-0648729-A1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP disclosed