SCHEMBL8635839

SCHEMBL8635839

Clc1cccc(Oc2ccc(OCC=C(Br)Br)c(Br)c2)c1

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PPARG P37231 2/20 0.39
PPARD Q03181 2/20 0.39
FFAR1 O14842 1/20 0.39
SLC6A4 P31645 3/20 0.39
MAOB P27338 1/20 0.39
AOC3 Q16853 1/20 0.39
SLC6A2 P23975 1/20 0.39
SLC6A3 Q01959 1/20 0.39
NPC1 O15118 3/20 0.37
WDR5 P61964 1/20 0.37
RAB9A P51151 1/20 0.37
LMNA P02545 2/20 0.36
HTR2A P28223 1/20 0.36
KCNH2 Q12809 1/20 0.36
KDM4E B2RXH2 1/20 0.35
RHEB Q15382 1/20 0.35
EGFR P00533 1/20 0.35
LCK P06239 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8633461 0.90 PPARG (0.39) PPARGPPARDFFAR1SLC6A4MAOB
SCHEMBL8636441 0.90 EPAS1 (0.38) NPC1RAB9ALMNAKDM4E
SCHEMBL8632883 0.88 PPARD (0.39) PPARGPPARDFFAR1SLC6A4MAOB
SCHEMBL8637045 0.88 PKM (0.37) NPC1RAB9ALMNA
SCHEMBL8634056 0.87 MAOB (0.38) MAOBNPC1RAB9ALMNAKDM4E
SCHEMBL8638567 0.84 SLC6A4 (0.38) PPARGPPARDFFAR1SLC6A4SLC6A2
SCHEMBL8634095 0.83 THRB (0.40) PPARGPPARDFFAR1SLC6A4MAOB
SCHEMBL8637041 0.83 AR (0.50) PPARGPPARDFFAR1SLC6A4MAOB
SCHEMBL8632023 0.80 PPARD (0.40) PPARDSLC6A4MAOBNPC1RAB9A
SCHEMBL8633981 0.79 EPAS1 (0.38) NPC1RAB9ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648729-B1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL CO (JP) 1998-07-15 EP disclosed
US-5698702-A INTERMEDIATES FOR INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-16 US disclosed
US-5530015-A Dihaloprene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient, and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-06-25 US disclosed
EP-0648729-A1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP disclosed