SCHEMBL8632883

SCHEMBL8632883

Clc1cccc(Oc2ccc(OCC=C(Br)Br)c(Cl)c2)c1

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 3/20 0.39
PPARG P37231 2/20 0.39
FFAR1 O14842 1/20 0.39
MRGPRX4 Q96LA9 2/20 0.39
SLC6A4 P31645 2/20 0.39
MAOB P27338 1/20 0.39
AOC3 Q16853 1/20 0.39
SLC6A2 P23975 1/20 0.39
SLC6A3 Q01959 1/20 0.39
TDP1 Q9NUW8 1/20 0.38
WDR5 P61964 1/20 0.38
PPARA Q07869 1/20 0.38
LMNA P02545 1/20 0.37
HTR2A P28223 1/20 0.36
KCNH2 Q12809 1/20 0.36
KMO O15229 1/20 0.36
KDM4E B2RXH2 1/20 0.36
RHEB Q15382 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8633165 0.89 TDP1 (0.37) PPARDPPARGSLC6A4TDP1PPARA
SCHEMBL8632023 0.88 PPARD (0.40) PPARDSLC6A4MAOBTDP1PPARA
SCHEMBL8635839 0.88 PPARG (0.39) PPARDPPARGFFAR1SLC6A4MAOB
SCHEMBL8634454 0.88 PPARD (0.40) PPARDPPARGFFAR1MRGPRX4SLC6A4
SCHEMBL8632796 0.88 TDP1 (0.41) PPARDPPARGFFAR1SLC6A4MAOB
SCHEMBL8413135 0.87 MAOB (0.45) PPARDPPARGFFAR1MRGPRX4SLC6A4
SCHEMBL8634095 0.84 THRB (0.40) PPARDPPARGFFAR1SLC6A4MAOB
SCHEMBL8637041 0.84 AR (0.50) PPARDPPARGFFAR1MRGPRX4SLC6A4
SCHEMBL8632081 0.78 PPARD (0.40) PPARDSLC6A4MAOBPPARALMNA
SCHEMBL8633461 0.78 PPARG (0.39) PPARDPPARGFFAR1SLC6A4MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648729-B1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL CO (JP) 1998-07-15 EP disclosed
US-5698702-A INTERMEDIATES FOR INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-16 US disclosed
US-5530015-A Dihaloprene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient, and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-06-25 US disclosed
EP-0648729-A1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP disclosed