SCHEMBL8635865

SCHEMBL8635865

FC(F)(F)c1cc(Oc2ccc(C3CCCCC3)cc2)ccc1OCC=C(Br)Br

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 4/20 0.36
HPGD P15428 2/20 0.33
HRH3 Q9Y5N1 2/20 0.33
KCNH2 Q12809 1/20 0.33
HAO1 Q9UJM8 1/20 0.33
CETP P11597 1/20 0.32
MEN1 O00255 1/20 0.32
NPC1 O15118 1/20 0.32
POLB P06746 1/20 0.32
RAB9A P51151 1/20 0.32
BLM P54132 1/20 0.32
KMT2A Q03164 1/20 0.32
GPR35 Q9HC97 1/20 0.32
TNK2 Q07912 1/20 0.32
PTGDR Q13258 1/20 0.32
CASP1 P29466 1/20 0.32
PPARG P37231 2/20 0.31
HTR2A P28223 1/20 0.31
LTA4H P09960 1/20 0.31
PPARA Q07869 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8635489 0.99 PTGDR2 (0.35) PTGDR2HPGDHRH3KCNH2HAO1
SCHEMBL8636876 0.89 PTGDR2 (0.36) PTGDR2HPGDHRH3KCNH2HAO1
SCHEMBL8633668 0.88 PTGDR2 (0.35) PTGDR2HPGDHRH3KCNH2HAO1
SCHEMBL8638939 0.82 SLC6A4 (0.41) KCNH2RAB9APPARGHTR2ALTA4H
SCHEMBL8635708 0.82 AR (0.39) PPARGPPARA
SCHEMBL8632656 0.81 KDM4E (0.37) MEN1POLBRAB9AKMT2A
SCHEMBL8637887 0.81 L3MBTL1 (0.39) PTGDR2MEN1RAB9ABLMKMT2A
SCHEMBL8635270 0.81 RXRA (0.35) LTA4H
SCHEMBL8635798 0.80 PPARG (0.43) PPARGPPARA
SCHEMBL8638264 0.80 LMNA (0.44) MEN1KMT2ALTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648729-B1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL CO (JP) 1998-07-15 EP claimed
US-5530015-A Dihaloprene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient, and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-06-25 US claimed
EP-0648729-A1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP claimed
EP-0648729-B1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL CO (JP) 1998-07-15 EP disclosed
US-5698702-A INTERMEDIATES FOR INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-16 US disclosed
US-5530015-A Dihaloprene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient, and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-06-25 US disclosed
EP-0648729-A1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP disclosed