Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 3/20 | 0.44 |
| ▸ | CTSK | P43235 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | LIPE | Q05469 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3968410 | 0.78 | MMP1 (0.42) | CTSSALDH1A1PKMSMN1; SMN2 | |
| SCHEMBL4323327 | 0.73 | PLA2G2C (0.44) | ALDH1A1 | |
| SCHEMBL1649294 | 0.73 | PLA2G2C (0.44) | ALDH1A1 | |
| SCHEMBL22507715 | 0.73 | L3MBTL1 (0.47) | CTSKL3MBTL1KMT2AMEN1TDP1 | |
| SCHEMBL21142831 | 0.73 | L3MBTL1 (0.47) | CTSKL3MBTL1KMT2AMEN1TDP1 | |
| SCHEMBL9728202 | 0.72 | ALDH1A1 (0.35) | CTSSKMT2AMEN1TDP1ALDH1A1 | |
| SCHEMBL9728204 | 0.72 | ALDH1A1 (0.35) | CTSSKMT2AMEN1TDP1ALDH1A1 | |
| SCHEMBL8635958 | 0.71 | SMN1; SMN2 (0.39) | KMT2AMEN1LMNAALDH1A1NPC1 | |
| SCHEMBL25106912 | 0.70 | L3MBTL1 (0.43) | CTSKL3MBTL1KMT2AMEN1TDP1 | |
| SCHEMBL9728155 | 0.70 | PKM (0.45) | CTSSPKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0852584-A1 | PEPTIDE DERIVATIVES HAVING ENDOTHELIN RECEPTOR ANTAGONISTIC ACTIVITY | Takeda Chemical Industries, Ltd. (JP) | 1998-07-15 | — | — | EP | disclosed |
| WO-1997011961-A1 | PEPTIDE DERIVATIVES HAVING ENDOTHELIN RECEPTOR ANTAGONISTIC ACTIVITY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-04-03 | — | — | WO | disclosed |