Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 3/20 | 0.39 |
| ▸ | DRD3 | P35462 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | CCKBR | P32239 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | LIPE | Q05469 | 2/20 | 0.36 |
| ▸ | SLC5A1 | P13866 | 4/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | GCGR | P47871 | 1/20 | 0.35 |
| ▸ | TOP2A | P11388 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8661826 | 0.88 | MCHR1 (0.39) | MCHR1OPRL1NOTUMDRD2DRD3 | |
| SCHEMBL9267232 | 0.80 | LIPE (0.46) | MCHR1NOTUMDRD2DRD3KCNH2 | |
| SCHEMBL8093681 | 0.76 | NOTUM (0.45) | MCHR1OPRL1NOTUMDRD2DRD3 | |
| SCHEMBL8786870 | 0.75 | NOTUM (0.43) | MCHR1OPRL1NOTUMDRD2DRD3 | |
| SCHEMBL8787181 | 0.75 | FFAR4 (0.49) | MCHR1OPRL1NOTUMDRD2DRD3 | |
| SCHEMBL8788951 | 0.74 | NOTUM (0.42) | MCHR1NOTUMDRD2DRD3KCNH2 | |
| SCHEMBL8556168 | 0.73 | DRD2 (0.44) | MCHR1OPRL1NOTUMDRD2DRD3 | |
| SCHEMBL8556361 | 0.73 | DRD2 (0.44) | MCHR1OPRL1NOTUMDRD2DRD3 | |
| SCHEMBL6507723 | 0.73 | DRD2 (0.42) | MCHR1OPRL1NOTUMDRD2DRD3 | |
| SCHEMBL8607080 | 0.73 | NOTUM (0.40) | MCHR1OPRL1NOTUMDRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828720-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED 5-HYDROXY-OXAZOLIDIN-4-ONE | ZENECA LIMITED (GB) | 1998-03-18 | — | — | EP | disclosed |
| EP-0763020-A1 | SUBSTITUTED PYRROLIDONE, THIAZOLIDONES OR OXAZOLIDONES AS HERBICIDES | ZENECA LIMITED (GB) | 1997-03-19 | — | — | EP | disclosed |
| WO-1996037483-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED 5-HYDROXY-OXAZOLIDIN-4-ONE | ZENECA LIMITED (GB) | 1996-11-28 | — | — | WO | disclosed |
| WO-1995033719-A1 | SUBSTITUTED PYRROLIDONE, THIAZOLIDONES OR OXAZOLIDONES AS HERBICIDES | ZENECA LIMITED (GB) | 1995-12-14 | — | — | WO | disclosed |