SCHEMBL8636192

SCHEMBL8636192

CC(C)c1cc(Oc2cccc(-c3ccccc3)c2)ccc1OCC=C(Cl)Cl

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 5/20 0.40
FFAR1 O14842 4/20 0.40
THRB P10828 3/20 0.37
RORC P51449 2/20 0.37
RXRA P19793 2/20 0.36
RXRB P28702 2/20 0.36
ACACB O00763 2/20 0.35
ACACA Q13085 2/20 0.35
THRA P10827 1/20 0.35
MEN1 O00255 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
RECQL P46063 1/20 0.34
KMT2A Q03164 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
GGPS1 O95749 1/20 0.34
PPARD Q03181 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8635018 0.92 THRB (0.40) THRBRORCTHRAMEN1CYP1A2
SCHEMBL8635552 0.89 FFAR4 (0.40) FFAR4FFAR1THRBRORCRXRA
SCHEMBL8635821 0.86 MEN1 (0.46) FFAR4FFAR1THRBRORCACACB
SCHEMBL8638487 0.86 THRB (0.40) FFAR1THRBRORCPPARD
SCHEMBL8632642 0.82 LTA4H (0.42) THRBRORCACACBACACAMEN1
SCHEMBL8635966 0.81 THRB (0.39) FFAR4THRBRORCACACBACACA
SCHEMBL8636070 0.81 PPARG (0.47) FFAR4FFAR1PPARD
SCHEMBL8635020 0.80 LTA4H (0.40) THRBRORCMEN1CYP1A2CYP3A4
SCHEMBL8632777 0.80 FFAR4 (0.40) FFAR4FFAR1THRBRXRARXRB
SCHEMBL8635790 0.80 PTGDR (0.37) FFAR4THRBRORCACACBACACA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648729-B1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL CO (JP) 1998-07-15 EP disclosed
US-5698702-A INTERMEDIATES FOR INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-16 US disclosed
US-5530015-A Dihaloprene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient, and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-06-25 US disclosed
EP-0648729-A1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP disclosed