Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 2/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KHK | P50053 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CHKA | P35790 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9538318 | 0.76 | SIGMAR1 (0.49) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL9048459 | 0.74 | SLC6A4 (0.50) | ACHEPOLBMEN1KMT2A | |
| SCHEMBL4715499 | 0.72 | KDM4E (0.61) | ALDH1A1HRH3KHKMAPTKDM4E | |
| SCHEMBL18590696 | 0.72 | CHKA (0.67) | SMN1; SMN2HRH1HRH3KHKLMNA | |
| SCHEMBL8636247 | 0.71 | DPP7 (0.61) | HRH1HRH3DRD2 | |
| SCHEMBL8781454 | 0.71 | CHRM2 (0.61) | ALDH1A1KHKLMNAMAPTKDM4E | |
| SCHEMBL8355347 | 0.70 | ACHE (0.57) | ACHEMEN1KMT2AITGB3ITGA2B | |
| SCHEMBL22857558 | 0.70 | CHKA (0.50) | ALDH1A1SMN1; SMN2HRH1HRH3KHK | |
| SCHEMBL12261943 | 0.70 | DRD4 (0.77) | HRH1HRH3POLBDRD2HTR2A | |
| SCHEMBL20159257 | 0.70 | ATM (0.49) | ALDH1A1SMN1; SMN2HRH1POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753659-A | ANTICOAGULANTS FOR BLOOD DISORDER, CARDIOVASCULAR DISORDER, THROMBOSIS, | ZENECA LIMITED (GB) | 1998-05-19 | — | — | US | disclosed |