Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.35 |
| ▸ | CTSG | P08311 | 2/20 | 0.35 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.35 |
| ▸ | CMA1 | P23946 | 2/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.35 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8883489 | 0.96 | PRSS1 (0.35) | SLC7A5POLBNPSR1MEN1KMT2A | |
| SCHEMBL8633548 | 0.91 | SLC7A5 (0.40) | SLC7A5POLBNPSR1MEN1KMT2A | |
| SCHEMBL8632463 | 0.76 | CYP1A2 (0.35) | KMT2ACYP1A2LMNA | |
| SCHEMBL8329548 | 0.75 | LTA4H (0.41) | SLC7A5POLBKMT2AMMP8CRHBP | |
| SCHEMBL8799066 | 0.74 | LMNA (0.39) | ADRB2ADRB1ADRB3MMP8CRHBP | |
| SCHEMBL8803294 | 0.74 | MMP8 (0.38) | PRSS1CTSGCTRB1CMA1MMP8 | |
| SCHEMBL8630768 | 0.73 | SLC7A5 (0.43) | SLC7A5KMT2ACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL8633545 | 0.70 | SLC7A5 (0.43) | SLC7A5POLBNPSR1MEN1KMT2A | |
| SCHEMBL26427016 | 0.70 | SLC7A5 (0.44) | SLC7A5CYP1A2CYP2D6CYP2C19ADRB2 | |
| SCHEMBL9785870 | 0.70 | NPC1 (0.43) | POLBNPSR1MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773465-A | Tartronic acids, their acetalic ethers and o-esters | DOMPE FARMACEUTICI S.P.A. (IT) | 1998-06-30 | — | — | US | disclosed |
| EP-0667850-B1 | TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS | DOMPE FARMACEUTICI SPA (IT) | 1997-05-28 | — | — | EP | disclosed |
| WO-1994010127-A1 | TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS | DOMPE' FARMACEUTICI S.P.A. (IT) | 1994-05-11 | — | — | WO | disclosed |