Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
| ▸ | PPID | Q08752 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8803294 | 0.89 | MMP8 (0.38) | LTA4HMMP8CRHBPCRHR2ALDH1A1 | |
| SCHEMBL8799774 | 0.89 | CYP17A1 (0.35) | LTA4HALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL8798766 | 0.88 | CYP3A4 (0.37) | ALDH1A1KMT2ATSHRPOLB | |
| SCHEMBL8799066 | 0.87 | LMNA (0.39) | LTA4HMMP8CRHBPCRHR2LMNA | |
| SCHEMBL8800048 | 0.85 | PGR (0.35) | LTA4HALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL8633548 | 0.83 | SLC7A5 (0.40) | MMP8CRHBPCRHR2ALDH1A1KMT2A | |
| SCHEMBL8798264 | 0.80 | TBXAS1 (0.37) | ALDH1A1 | |
| SCHEMBL28134045 | 0.79 | MMP8 (0.42) | LTA4HMMP8SYKCRHBPCRHR2 | |
| SCHEMBL8798456 | 0.78 | CYP4F2 (0.32) | ALDH1A1TSHR | |
| SCHEMBL27540505 | 0.77 | LTA4H (0.43) | LTA4HSYKALDH1A1PPARAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5908863-A | ANTIGROWTH AGENT FOR BONES | DOMPE' S.P.A. (IT) | 1999-06-01 | — | — | US | disclosed |
| EP-0792878-A2 | Geminal carboxylic acids and esters thereof, pharmaceutical formulations containing them useful in the treatment of bone dysmetabolism | Dompé S.P.A. (IT) | 1997-09-03 | — | — | EP | disclosed |