Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | CTSK | P43235 | 2/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | CTSG | P08311 | 1/20 | 0.36 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.36 |
| ▸ | CMA1 | P23946 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8799066 | 0.94 | LMNA (0.39) | MMP8TDP1TAAR1CTSKCTSS | |
| SCHEMBL8329548 | 0.89 | LTA4H (0.41) | MMP8CRHBPCRHR2LTA4HALDH1A1 | |
| SCHEMBL8798264 | 0.88 | TBXAS1 (0.37) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL8799959 | 0.84 | ALDH1A1 (0.39) | CTSKCTSSSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL8798973 | 0.83 | FKBP1A (0.37) | ALDH1A1 | |
| SCHEMBL8633548 | 0.81 | SLC7A5 (0.40) | MMP8TDP1SMN1; SMN2CRHBPCRHR2 | |
| SCHEMBL8798456 | 0.81 | CYP4F2 (0.32) | ALDH1A1 | |
| SCHEMBL8803290 | 0.81 | LTA4H (0.46) | MMP8TDP1TAAR1CTSKCTSS | |
| SCHEMBL8800134 | 0.80 | CYP4F2 (0.36) | CTSKPRSS1L3MBTL1 | |
| SCHEMBL8798766 | 0.80 | CYP3A4 (0.37) | SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792878-A2 | Geminal carboxylic acids and esters thereof, pharmaceutical formulations containing them useful in the treatment of bone dysmetabolism | Dompé S.P.A. (IT) | 1997-09-03 | — | — | EP | disclosed |