Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
| ▸ | TACR2 | P21452 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SHBG | P04278 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8639820 | 0.86 | OPRM1 (0.35) | OPRL1OPRM1OPRD1OPRK1ADRA2A | |
| SCHEMBL8639794 | 0.86 | DRD2 (0.38) | OPRL1OPRM1OPRD1OPRK1SLC6A2 | |
| SCHEMBL8643030 | 0.84 | ALDH1A1 (0.41) | OPRL1OPRM1OPRD1OPRK1ALDH1A1 | |
| SCHEMBL8640570 | 0.83 | OPRL1 (0.38) | OPRL1OPRM1OPRD1OPRK1SLC6A2 | |
| SCHEMBL8637057 | 0.80 | SLC6A3 (0.37) | SLC6A2SLC6A4SLC6A3TP53CYP3A4 | |
| SCHEMBL8641145 | 0.74 | OPRL1 (0.36) | OPRL1OPRM1OPRD1OPRK1CYP3A4 | |
| SCHEMBL8641146 | 0.74 | OPRL1 (0.36) | OPRL1OPRM1OPRD1OPRK1CYP3A4 | |
| SCHEMBL18910942 | 0.72 | OPRL1 (0.56) | OPRL1OPRM1OPRD1OPRK1SLC6A2 | |
| SCHEMBL11166115 | 0.72 | BCHE (0.57) | OPRL1ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL18910938 | 0.71 | OPRL1 (0.55) | OPRL1OPRM1OPRD1OPRK1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0571652-B1 | Liquid crystalline substituted dihydrobenzene derivatives | CITIZEN WATCH CO LTD (JP) | 1998-08-05 | — | — | EP | disclosed |
| US-5342546-A | Liquid crystal compositions | L.C.C. CONSULTANTS CO., LTD. (JP) | 1994-08-30 | — | — | US | disclosed |
| EP-0571652-A1 | Liquid crystalline substituted dihydrobenzene derivatives | L.C.C. CONSULTANTS CO., LTD. (JP) | 1993-12-01 | — | — | EP | disclosed |