Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.37 |
| ▸ | GCGR | P47871 | 1/20 | 0.33 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.32 |
| ▸ | CHRNG | P07510 | 1/20 | 0.32 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | CHRND | Q07001 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8639794 | 0.85 | DRD2 (0.38) | SLC6A3SLC6A4SLC6A2DRD2 | |
| SCHEMBL8636331 | 0.80 | OPRL1 (0.42) | SLC6A3SLC6A4SLC6A2SPHK2TP53 | |
| SCHEMBL8639820 | 0.80 | OPRM1 (0.35) | SLC6A3SLC6A4SLC6A2DRD2CYP3A4 | |
| SCHEMBL8640570 | 0.80 | OPRL1 (0.38) | SLC6A3SLC6A4SLC6A2DRD2MEN1 | |
| SCHEMBL8643030 | 0.78 | ALDH1A1 (0.41) | MEN1TSHRHTTKMT2A | |
| SCHEMBL8640293 | 0.75 | CYP3A4 (0.33) | SLC6A3SLC6A4SLC6A2CHRNA1CHRNG | |
| SCHEMBL8640296 | 0.75 | CYP3A4 (0.33) | SLC6A3SLC6A4SLC6A2CHRNA1CHRNG | |
| SCHEMBL10798909 | 0.71 | OPRM1 (0.39) | SLC6A3SLC6A4SLC6A2CHRNA1CHRNG | |
| SCHEMBL2457777 | 0.69 | DRD2 (0.41) | SLC6A3SLC6A4SLC6A2CHRNA1CHRNG | |
| SCHEMBL23215170 | 0.68 | SLC6A3 (0.47) | SLC6A3SLC6A4SLC6A2CHRNA1CHRNG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0571652-B1 | Liquid crystalline substituted dihydrobenzene derivatives | CITIZEN WATCH CO LTD (JP) | 1998-08-05 | — | — | EP | disclosed |
| US-5342546-A | Liquid crystal compositions | L.C.C. CONSULTANTS CO., LTD. (JP) | 1994-08-30 | — | — | US | disclosed |
| EP-0571652-A1 | Liquid crystalline substituted dihydrobenzene derivatives | L.C.C. CONSULTANTS CO., LTD. (JP) | 1993-12-01 | — | — | EP | disclosed |