SCHEMBL8663248

SCHEMBL8663248

CCCc1scc(C(OC(C)=O)C(C)F)c1S(=O)(=O)NC(C)(C)C

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8636609 0.76 GAA (0.31)
SCHEMBL8111692 0.72 NSD2 (0.36) MAPTNPSR1
SCHEMBL8106979 0.65 ALOX5AP (0.35)
SCHEMBL9020663 0.64 ALDH1A1 (0.35) MAPTNPSR1
SCHEMBL8641780 0.63
SCHEMBL8640399 0.61 CA2 (0.30)
SCHEMBL9021100 0.61 USP30 (0.32) MAPTNPSR1
SCHEMBL8637572 0.61 KDM4E (0.32) MAPTNPSR1
SCHEMBL9523006 0.61 MAPT (0.37) MAPTNPSR1
SCHEMBL7806538 0.60 USP30 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5726127-A Thiophenesulfonylurea derivatives and herbicidal composition containing the same KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1998-03-10 US disclosed