Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CCNC | P24863 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.36 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8355478 | 0.98 | OPRM1 (0.40) | OPRM1OPRL1HSD11B1LMNANPSR1 | |
| SCHEMBL5200961 | 0.87 | HSD11B1 (0.46) | OPRM1OPRL1HSD11B1LMNANPSR1 | |
| Hydrochloric Acid SCHEMBL6504195 | 0.85 | HSD11B1 (0.45) | OPRM1OPRL1HSD11B1LMNANPSR1 | |
| SCHEMBL7338024 | 0.84 | AKR1C1 (0.47) | OPRM1HSD11B1LMNANPSR1CYP2D6 | |
| SCHEMBL89807 | 0.84 | LMNA (0.51) | OPRM1OPRL1HSD11B1LMNANPSR1 | |
| SCHEMBL10002396 | 0.84 | LMNA (0.47) | OPRM1OPRL1HSD11B1LMNANPSR1 | |
| Hydrochloric Acid SCHEMBL8356143 | 0.83 | AKR1C1 (0.46) | OPRM1HSD11B1LMNANPSR1CYP2D6 | |
| SCHEMBL5201676 | 0.82 | LMNA (0.51) | OPRM1OPRL1HSD11B1LMNANPSR1 | |
| SCHEMBL476403 | 0.82 | OPRM1 (0.58) | OPRM1OPRL1HSD11B1HDAC1 | |
| SCHEMBL7467936 | 0.81 | OPRM1 (0.45) | OPRM1OPRL1HSD11B1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824690-A | TREATING ASTHMA, COUGH | HOECHST MARION ROUSSEL INC. (US) | 1998-10-20 | — | — | US | disclosed |