Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | NCF1 | P14598 | 1/20 | 0.36 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 5/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | LSS | P48449 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8634130 | 0.83 | ITGB3 (0.39) | ITGB3ITGA2BMEN1KMT2AALDH1A1 | |
| SCHEMBL7396531 | 0.72 | ITGB3 (0.49) | ITGB3ITGA2BMEN1KMT2A | |
| SCHEMBL8701209 | 0.66 | L3MBTL1 (0.37) | ITGB3ITGA2BMEN1KMT2AADRB2 | |
| SCHEMBL8778807 | 0.66 | KMT2A (0.44) | ITGB3ITGA2BMEN1KMT2AALDH1A1 | |
| SCHEMBL8633916 | 0.65 | ADRB2 (0.35) | ITGB3ITGA2BADRB2NCF1PLD1 | |
| Acetic Acid SCHEMBL27482977 | 0.64 | ADRB2 (0.76) | ALDH1A1CYP3A4CYP2C9CYP2C19ADRB2 | |
| SCHEMBL8631574 | 0.64 | HRH3 (0.54) | ITGB3ITGA2BALDH1A1CYP2C9ADRB2 | |
| SCHEMBL171845 | 0.63 | MAPT (0.63) | MEN1KMT2AALDH1A1NPSR1ADRB2 | |
| SCHEMBL7119420 | 0.63 | MAPT (0.45) | MEN1KMT2AF10RORCMAPT | |
| SCHEMBL6791781 | 0.63 | ITGB3 (0.57) | ITGB3ITGA2BMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753659-A | ANTICOAGULANTS FOR BLOOD DISORDER, CARDIOVASCULAR DISORDER, THROMBOSIS, | ZENECA LIMITED (GB) | 1998-05-19 | — | — | US | disclosed |