Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.32 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.32 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.31 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8634309 | 0.84 | SLC9A1 (0.31) | — | |
| SCHEMBL7764849 | 0.81 | SLC9A1 (0.51) | — | |
| SCHEMBL8538752 | 0.80 | SLC9A1 (0.39) | — | |
| SCHEMBL8635246 | 0.78 | LMNA (0.35) | — | |
| SCHEMBL27373283 | 0.77 | FLT1 (0.35) | — | |
| SCHEMBL8631189 | 0.76 | MEN1 (0.31) | — | |
| SCHEMBL8635203 | 0.76 | HSP90AA1 (0.35) | THRBTHRA | |
| SCHEMBL8634504 | 0.76 | FLT1 (0.38) | — | |
| SCHEMBL8634234 | 0.76 | MEN1 (0.36) | — | |
| SCHEMBL8667426 | 0.75 | SLC9A1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739142-A | 4-aminobenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-04-14 | — | — | US | disclosed |