Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 8/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | TNKS | O95271 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12020787 | 0.86 | — | — | |
| SCHEMBL863108 | 0.85 | PDE4D (0.41) | MAPTALDH1A1LMNAKDM4ERAB9A | |
| SCHEMBL10237130 | 0.85 | PDE4D (0.37) | MAPTALDH1A1LMNAKDM4ERAB9A | |
| SCHEMBL14130855 | 0.80 | TACR1 (0.38) | MAPTALDH1A1NPSR1LMNAATM | |
| SCHEMBL6100934 | 0.75 | S100A4 (0.34) | MAPTALDH1A1NPSR1LMNAATM | |
| SCHEMBL6100932 | 0.75 | S100A4 (0.34) | MAPTALDH1A1NPSR1LMNAATM | |
| SCHEMBL6099876 | 0.74 | LMNA (0.40) | MAPTALDH1A1NPSR1LMNAATM | |
| SCHEMBL6097459 | 0.74 | S100A4 (0.47) | MAPTALDH1A1NPSR1LMNATACR1 | |
| SCHEMBL6106397 | 0.74 | ALDH1A1 (0.51) | MAPTALDH1A1NPSR1LMNAKDM4E | |
| Water SCHEMBL6101423 | 0.73 | S100A4 (0.46) | MAPTALDH1A1NPSR1LMNATACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741908-A | Process for reparing imidazoquinolinamines | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-04-21 | — | — | US | disclosed |
| US-5693811-A | Process for preparing tetrahdroimidazoquinolinamines | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-12-02 | — | — | US | disclosed |