Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.42 |
| ▸ | F10 | P00742 | 13/20 | 0.41 |
| ▸ | CCNC | P24863 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8637204 | 0.88 | HRH3 (0.44) | HRH3F10CCNCCDK8 | |
| SCHEMBL8632715 | 0.78 | HRH3 (0.43) | HRH3F10CCNCCDK8 | |
| SCHEMBL7494742 | 0.76 | F10 (0.38) | F10 | |
| SCHEMBL7328358 | 0.76 | F10 (0.38) | F10 | |
| SCHEMBL8637465 | 0.76 | CYP2C9 (0.45) | HRH3F10 | |
| SCHEMBL8637208 | 0.74 | F10 (0.49) | HRH3F10CCNCCDK8 | |
| SCHEMBL7396282 | 0.73 | F10 (0.39) | F10 | |
| SCHEMBL8637213 | 0.72 | F10 (0.44) | HRH3F10CCNCCDK8 | |
| SCHEMBL8081153 | 0.70 | LMNA (0.56) | — | |
| SCHEMBL4711656 | 0.70 | ITGB3 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753659-A | ANTICOAGULANTS FOR BLOOD DISORDER, CARDIOVASCULAR DISORDER, THROMBOSIS, | ZENECA LIMITED (GB) | 1998-05-19 | — | — | US | disclosed |
| US-5728701-A | INHIBIT PLATELET AGGREGATION | ZENECA LIMITED (GB) | 1998-03-17 | — | — | US | disclosed |